ZyVersa Therapeutics Announces Publishes Scientific Paper in Frontiers in Molecular Neuroscience

April 29, 2024

DENVER, Colo., Apr 29, 2024 (247marketnews.com)- ZyVersa Therapeutics, Inc. (Nasdaq:ZVSA) stated that researchers from the University of Miami Miller School of Medicine and inventors of Inflammasome ASC Inhibitor IC 100 published a scientific paper “Extracellular vesicles mediate inflammasome signaling in the brain and heart of Alzheimer’s disease mice,” in the peer-reviewed journal, Frontiers in Molecular Neuroscience, highlighting how inflammasome-mediated inflammation in Alzheimer’s disease can trigger inflammation in the heart, which summarizes research evaluating serum and tissue cultures from an AD mouse model.

“Our data provide evidence that there is a neural-cardiac axis mediated by EVs in AD. Therefore, inflammasomes may provide a novel therapeutic target for the treatment of cardiac comorbidities in AD and beyond,” commented Juan Pablo de Rivero Vaccari, Associated Professor of Neurological Surgery and The Miami Project to Cure Paralysis at the University of Miami.

“This research reinforces the importance of attenuating activation of multiple types of inflammasomes that govern the inflammatory response in AD and mediating systemic inflammatory signals in EVs to control the spread of damaging inflammation to cardiovascular and other cells,” stated Stephen C. Glover, ZyVersa’s Co-founder, Chairman, CEO, and President. “ZyVersa’s Inflammasome ASC inhibitor IC 100 is designed to inhibit formation of multiple types of inflammasomes to attenuate initiation of the inflammatory cascade and to inhibit their associated ASC specks to reduce spread and perpetuation of damaging inflammation.”

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