MAIA Biotechnology Reports Positive Phase 2 THIO-101 Clinical Trial Updates

July 23, 2024

DENVER, Colo., Jul 23, 2024 (247marketnews.com)- MAIA Biotechnology, Inc., (NYSE:MAIA) reported positive treatment updates from its Phase 2 THIO-101 clinical trial, evaluating THIO sequenced with the immune checkpoint inhibitor (CPI) cemiplimab (Libtayo) in patients with advanced non-small cell lung cancer (NSCLC) who failed two or more standard-of-care therapy regimens.

Six patients remain on treatment, following at least 12 months of therapy, and completed up to 21 cycles with THIO, followed by cemiplimab, which has been well tolerated throughout the trial, with much lower toxicity compared to standard-of care treatments.

“Our longest treated patient so far has completed 21 cycles of THIO sequenced with a CPI, and 6 patients who have crossed the 12-month survival follow-up are continuing the treatment,” said Vlad Vitoc, M.D., Chairman and Chief Executive Officer of MAIA. “With current therapies, second-line patients’ treatment duration is usually around 3-4 months1 and third-line is even lower than that. It is very encouraging to see that our patients can remain on treatment for much longer. The ongoing benefits of THIO in longer-term patients are particularly notable, signifying THIO’s potential as a durable and efficacious treatment for advanced NSCLC patients faced with limited options.”

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