Neumora Therapeutics Announces Clinical Hold of Phase 1 NMRA-266 Study
WATERTOWN, Mass., April 15, 2024 (GLOBE NEWSWIRE) — Neumora Therapeutics, Inc. (Nasdaq:NMRA), a clinical-stage biopharmaceutical company with a therapeutics pipeline consisting of seven clinical and pre-clinical brain disease programs, today announced that the Phase 1 trial of NMRA-266 has been placed on clinical hold by the U.S. Food and Drug Administration (FDA). NMRA-266 is a positive allosteric modulator (PAM) of the M4 muscarinic receptor and is part of the Company’s M4 PAM franchise. The clinical hold determination follows recently available pre-clinical data showing convulsions in rabbits.