In preclinical studies, CHS-1000 shows a high affinity for human ILT4, reverses ILT4-mediated immunosuppressive functions, leading to activation of immune cells and increased cytokine secretion
Mechanism may enhance antitumor responses with immunotherapy
First novel immuno-oncology product candidate discovered and developed by Coherus
– The CHS-1000 IND submission is planned for Q2 2024 –

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