Closing Bell Heat Check: Biotech Breakouts, Reverse Mergers & Moonshot Setups Heading into After-Hours

August 1, 2025

DENVER, Colo., Aug 01, 2025 (247marketnews.com)- As the final trading hour approaches, watch for names building into potential breakouts, or setting up for extended moves after-hours.

4D Molecular (NASDAQ:FDMT) is having its strongest day since its rally began in April, fueled by renewed enthusiasm for its lead asset 4D-150, a gene therapy candidate for diabetic macular edema (DME).

Positive 52-week and 60-week clinical data and regulatory alignment with the European Medicines Agency (EMA) were presented at the 43rd Annual American Society of Retina Specialists (ASRS) Meeting by David Almeida, M.D., MBA, Ph.D., Erie Retina Research.

Siyata Mobile’s (NASDAQ:SYTA) pending $185M reverse merger with Core Gaming is turning heads. The transformation from rugged mobile hardware to AI-powered content and entertainment delivery makes this one of the most compelling small-cap pivot plays of the year.

Short interest remains elevated, and if Nasdaq approval hits, SYTA could reprice quickly. Definitely one to monitor after-hours for filings or insider buying updates.

Rocket (NYSE:RKT) came close to a new 2025 high today before cooling off. The underlying fundamentals remain strong, with Q2 2025 adjusted revenue of $1.34B, $75M in adjusted net income, and $172M in adjusted EBITDA, all above the high end of guidance.

Despite a challenging macro for mortgages, Rocket’s diverse fintech ecosystem, covering real estate, title, and personal finance, adds defensive appeal.

Reddit’s (NASDAQ:RDDT) surprise Q2 profit of $0.45 EPS (versus a $0.06 loss a year ago) caught many off guard. It hasn’t exploded yet, but the move could be just getting started as institutional investors reconsider long-term monetization.

This is one to watch after-hours for insider activity, options flow, or analyst upgrades.

Venu (NYSE:VENU) is still flirting with a $14 breakout, VENU is consolidating tightly. A push past that level opens the door for a run toward the $22.30 target from Cenorium AG.

CEO J.W. Roth invested $5M of his own capital, with plans to increase it to $20M, into the company’s NNN FireSuites, which offer 11% projected cap rates and no exposure to property taxes, insurance, or maintenance.

This is a REIT-style hybrid with live entertainment upside and short squeeze potential, don’t be surprised if this one lights up after-hours on technical momentum.

LOBO EV (NASDAQ:LOBO) made multiple intraday runs and could be setting up for another wave higher before the bell.

Alphatec (NASDAQ:ATEC) hit a new 52-week high of $13.89 today after turning a corner with $0.02 EPS, $185.54M in revenue (beating by $6.69M), and guiding to $742M for 2025 on record EBITDA and an expanding surgical ecosystem.

iRhythm (NASDAQ:IRTC) raised its 2025 revenue outlook to $730M, citing strong momentum across core and emerging channels. Expect this to attract analysts and momentum buyers after-hours, especially if guidance commentary is reiterated in any fireside chats.

Workiva (NYSE:WK) surged today after raising 2025 guidance to $873M and citing improving operating margins. The stock is back on institutional radars, and traders will be watching for after-market continuation volume.

With biotech, small-cap tech, and real estate plays firing, this afternoon is not the time to look away. The FDMT and SYTA stories both have real meat, and names like VENU and LOBO EV offer high-beta setups into the close.

Stay locked into 24/7 Market News for after-hours alerts, news drops, and gap-up coverage first thing tomorrow.

Please click here to read Cenorium’s full Venu analyst report on 247marketnews.com.

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